Events

SHERIDAN, WYOMING – July 1, 2025 – Pfizer has announced the termination of its Phase II trial evaluating the investigational CD47-targeting fusion protein maplirpacept in diffuse large B-cell lymphoma (DLBCL), citing persistent recruitment difficulties that prevented the study from meeting enrollment targets. The decision, which affects a program inherited through the company’s $2.26 billion acquisition of Trillium Therapeutics in 2021, underscores ongoing challenges in advancing CD47 inhibitors while highlighting Pfizer’s continued commitment to its hematologic oncology pipeline.

Recruitment Roadblocks Halt Mid-Stage Development

SHERIDAN, WYOMING – July 1, 2025 – A late surge of acquisitions in June has reenergized pharmaceutical M&A activity, with six major deals announced that propelled first-half 2025 totals to 32 transactions across the industry. This burst of dealmaking, highlighted by BioNTech’s $1.25 billion acquisition of CureVac and Eli Lilly’s $1.3 billion buyout of Verve Therapeutics, has analysts optimistic that the sector’s cautious stance may finally be easing.

Resilient M&A Amid Regulatory Uncertainty

The first half of 2025 was marked by significant headwinds for dealmakers, including political and regulatory turbulence. The deal flow in the first half was overall “relatively steady but cautious,” PwC said in the firm’s mid-year outlook, published June 18. There were about 32 deals in the biopharma space recorded for the first half, according to data from S&P Capital IQ and analyzed by BioSpace.

SHERIDAN, WYOMING – July 1, 2025 – A groundbreaking collaboration that delivered a custom-made CRISPR therapy to a nine-month-old patient with CPS1 deficiency has ignited optimism that ultrarare diseases could soon be addressed on a broader scale, thanks to advances in delivery systems, precision gene editing, and regulatory pathways.

KJ’s treatment—the first of its kind—was made possible through contributions from Acuitas Therapeutics, Aldevron, and Integrated DNA Technologies (IDT), which manufactured and shipped the key components free of charge. The success has prompted key industry figures to ask: can this model be repeated to address the thousands of ultrarare conditions affecting patients worldwide?

The Case for Platform Technologies

SHERIDAN, WYOMING – July 1, 2025 – A wave of pivotal FDA decisions in June 2025 is reshaping key segments of the pharmaceutical landscape, with new approvals spanning respiratory syncytial virus (RSV) vaccines, advanced cancer treatments, and the first-ever antiviral for acute hepatitis C. These regulatory moves not only expand therapeutic options for patients but also set the stage for intensified competition in critical markets, underscoring strategic opportunities for companies across the biopharmaceutical sector.

Moderna and Merck Drive RSV Market Expansion

SHERIDAN, WYOMING – July 1, 2025 – spoga+gafa 2025 has firmly established outdoor living as a central pillar of the modern lifestyle economy, setting new benchmarks for the global garden and outdoor sector. Drawing around 26,000 trade visitors from more than 100 countries and over 1,600 exhibitors, the world’s leading trade fair for garden lifestyle & BBQs concluded on a high note, despite ongoing economic uncertainties and geopolitical headwinds. This strong turnout confirms spoga+gafa’s position as the leading platform of the garden industry.

International Momentum Signals Market Resilience

SHERIDAN, WYOMING – July 1, 2025 – Ricoh has announced the launch of the new Pro™ C5400 series for color production printing, introducing systems that combine increased production speed with enhanced user-friendliness. Designed to meet the diverse needs of commercial print service providers and in-house print centers, the Pro C5400 series builds on the output speed and excellent paper handling of the previous Ricoh Pro™ C5310S/C5300S/Pro C5300SL models, delivering significant improvements in overall performance.

Expanded Production Capabilities for Evolving Demands

The Pro C5400 series offers a range of advanced features to help customers meet market demands for high-quality, short-run jobs:

SHERIDAN, WYOMING – June 27, 2025 – Jakarta will become Southeast Asia’s leading hub for the woodworking, furniture manufacturing, and hardware sectors this September, as three major exhibitions—interzum jakarta, International Hardware Fair Indonesia, and IFMAC & WOODMAC—unite in a groundbreaking 3-in-1 format at JIExpo Kemayoran from September 24–27, 2025. This unique collaboration brings the entire furniture and woodworking industry value chain together under one roof, promising to accelerate cross-sector innovation, strengthen regional supply chains, and position Indonesia as a key player in the global manufacturing landscape.

A Strategic Platform for Cross-Sector Collaboration

For the first time in Southeast Asia, professionals can access the full spectrum of the furniture production and hardware industries with a single ticket. The event will integrate:

SHERIDAN, WYOMING – June 27, 2025 – Koelnmesse has announced a robust new ten-year corporate strategy after closing its centenary year with impressive financial results, signaling confidence in its growth trajectory despite global market challenges. The renowned international trade fair organizer recorded EUR 365.8 million in turnover and EUR 21.3 million in profit for 2024, hosting 76 events worldwide and welcoming over 2.1 million visitors from 197 countries.

Strong Financials and International Expansion Drive Momentum

SHERIDAN, WYOMING - June 27, 2025 - A new wave of breakthroughs in 3D printing materials for dental applications is redefining the capabilities of digital dentistry, enabling practices to deliver faster, more precise, and highly customized patient care while maintaining clinical safety and efficiency.

Dental 3D printing has evolved rapidly over the past decade, with materials innovation playing a central role in expanding what's possible-from same-day night guards to definitive crowns. The industry's shift toward specialized, biocompatible resins developed exclusively for dental workflows is setting new standards in prosthetics quality, workflow integration, and patient outcomes.

A Decade of Material Evolution Unlocks Clinical Versatility

SHERIDAN, WYOMING - June 27, 2025 - Digital dentures are transforming prosthetic dentistry, delivering a precise, efficient, and patient-friendly alternative to traditional dentures. By leveraging advanced technologies like 3D scanning, CAD/CAM design, and 3D printing, companies like SprintRay are pioneering a workflow that enhances comfort, fit, and aesthetics for patients, while reducing errors and appointment times for dental professionals.

Embracing Cutting-Edge Technology for Superior Results

SHERIDAN, WYOMING - June 27, 2025 - Dental laboratories worldwide are set to benefit from a powerful advancement as SprintRay's Apex Base and Apex Teeth resins have been officially validated for use on Carbon's M-Series 3D printers, unlocking new levels of precision, aesthetics, and operational efficiency in digital denture fabrication.

Strengthening a Strategic Collaboration

The validation marks the latest milestone in the ongoing collaboration between SprintRay and Carbon, building on the prior success of SprintRay's OnX Tough 2 resin. By deepening this partnership, both companies are reinforcing their shared commitment to transforming dental workflows through innovative technologies designed to improve productivity and clinical outcomes.

SHERIDAN, WYOMING – June 27, 2025 – Ricoh Europe has unveiled its latest innovation in textile printing technology, the XTF D430, a compact, affordable, and versatile direct-to-film (DTF) system designed to empower small to medium Print Service Providers (PSPs) across EMEA with unprecedented application creativity, operational flexibility, and stable production quality.

The XTF D430 enables PSPs to deliver a broad range of customized textile products—from t-shirts and hoodies to hats and shoes—while keeping investment costs low and maintaining exceptional quality standards. This new solution continues Ricoh’s mission to transform digital textile printing, providing tools that meet the market’s demand for agile, on-demand production without compromising on durability or color accuracy.

SHERIDAN, WYOMING - June 27, 2025 - In a landmark effort to expand access to high-quality oral healthcare, Dentsply Sirona, the world's largest diversified manufacturer of professional dental products and technologies, has successfully completed a week-long dental expedition in partnership with Brazilian NGO Project 32. This initiative, part of Dentsply Sirona's sustainability program "BEYOND: Taking Action for a Brighter World," brought advanced, free dental care to remote Amazonian communities, combining on-site and digital expertise to reach some of Brazil's most underserved populations.

Connecting Dentists and Patients Through Digital Dentistry

SHERIDAN, WYOMING - June 24, 2025 - Dentsply Sirona has officially opened registration for DS World Las Vegas 2025, its flagship clinical education event, returning to the MGM Grand from September 25-27. Designed to empower dental professionals through innovation and knowledge-sharing, the event will spotlight Dentsply Sirona's Connected Dentistry proposition, with a strategic focus on digital integration, workflow optimization, and patient care advancement.

Driving Practice Efficiency Through Connected Technologies

This year's DS World will immerse attendees in the rapidly evolving landscape of digital dentistry, with a strong emphasis on data-driven, integrated technologies. From AI-powered tools to cloud-based collaboration, participants will gain actionable insights into how Dentsply Sirona's solutions-such as the DS Core platform-are reshaping modern dental practices.

Attendees will explore:

SHERIDAN, WYOMING - June 24, 2025 - Dentsply Sirona has announced a major upgrade to its Primeprint Solution, enhancing 3D printing speeds and introducing the fully autonomous Primeprint Nitrogenerator to streamline post-processing workflows for dental labs and practices. These innovations are designed to improve throughput, reduce manual tasks, and reinforce the company's commitment to Connected Dentistry.

Faster Splint Manufacturing Enhances Efficiency

The upgraded Primeprint delivers twice the speed for splint production, notably impacting applications involving Primeprint Splint, Primeprint Splint SF, Primeprint Splint ST, as well as Model and Tray applications. Nightguards, for example, can now be produced in approximately 14 minutes, significantly reducing turnaround times.

SHERIDAN, WYOMING - June 24, 2025 - Dentsply Sirona is celebrating a decade of clinical impact with WaveOne® Gold, the company's flagship reciprocating file system that has revolutionized endodontic workflows globally. Launched in 2015, WaveOne® Gold continues to deliver procedural consistency and confidence for clinicians, backed by scientific validation and a legacy of innovation in root canal therapy.

Decade-Long Impact on Clinical Efficiency and Confidence

Since its debut, WaveOne® Gold has reshaped the practice of endodontics by offering a simplified single-file approach to root canal shaping. Leveraging a proprietary gold heat-treated alloy, the system enhances flexibility and fatigue resistance-key attributes that improve procedural predictability and reduce chair time. Used in more than 130 countries, WaveOne® Gold has become a staple in dental practices worldwide.

SHERIDAN, WYOMING – June 24, 2025 – Dentsply Sirona, in collaboration with the American Association for Dental, Oral, and Craniofacial Research (AADOCR) and the SCADA Alumni Association, has announced a new initiative to fund early-career research in dental, oral, and craniofacial biology. The AADOCR SCADA/Dentsply Sirona Research Award will provide up to $10,000 to emerging dentist-scientists pursuing academic careers.

New award aims to strengthen academic pathways in dental research

The new award was created to support dentist-scientists, including SCADA program alumni, in their research careers. The award’s immediate goal is to support early-stage dentist-scientists such as post-doctoral scholars and pre-tenure faculty members, with a long-term objective of increasing the number of successfully funded dentist-scientists at the higher ranks in science and academia in the fields of dental, oral, and craniofacial (DOC) biology.

SHERIDAN, WYOMING - June 24, 2025 - Dentsply Sirona is calling on the global dental industry to strengthen its commitment to sustainable packaging, aligning with World Environment Day 2025 and accelerating efforts under its "BEYOND: Taking Action for a Brighter World" strategy. As part of its Healthy Planet pillar, the company aims to make all of its packaging recyclable by 2030, reinforcing its leadership role in advancing environmentally responsible practices across dental care.

Driving Sustainable Packaging Innovation

Packaging accounts for a significant share of waste in the dental industry and beyond. In the U.S., it makes up 63% of municipally collected garbage, while in dentistry it is the largest contributor to plastic waste. Dentsply Sirona is actively addressing this issue by implementing circular economy principles-reduce, reuse, and recycle-into its packaging systems.

This includes:

SHERIDAN, WYOMING - June 24, 2025 - Dentsply Sirona is reinforcing its commitment to sustainability in dentistry by co-sponsoring the FDI World Dental Federation's 2025 Sustainability in Dentistry Summit and supporting the launch of a new Massive Open Online Course (MOOC) focused on actionable sustainable practices.

The summit, taking place virtually on June 5 and 6 from 10:00 to 11:30 AM EST / 04:00 to 05:30 CEST, aims to bring together global dental professionals to explore practical solutions for a more sustainable future in dentistry. The event also marks the debut of FDI's second free MOOC, "Tackling Common Challenges to Sustainable Dentistry." Registration is free of charge, and Dentsply Sirona is encouraging dental professionals, students, and industry stakeholders worldwide to participate.

Driving Engagement Through Strategic Partnerships

SHERIDAN, WYOMING – June 24, 2025 – Ricoh has announced that DATEV eG, one of Germany’s leading IT service providers, has invested in the Ricoh Pro™ VC40000 to boost productivity and set new standards in print production across its high-volume output operations.

With over one billion printed pages annually, DATEV operates a powerful Digital & Print Solution Center to support communication between businesses and their clients and employees. The addition of Ricoh’s high-speed inkjet system is expected to enhance throughput, reduce turnaround times, and drive efficiency in both standard and high-quality print applications.

Driving Performance Through Technology Integration