SHERIDAN, WYOMING – July 29, 2025 – Roche is accelerating its multi-modal approach to Alzheimer’s disease, unveiling new data at the Alzheimer’s Association International Conference (AAIC) that spotlight the therapeutic potential of trontinemab and the diagnostic promise of its Elecsys® pTau217 blood test. Together, these innovations signal a possible shift toward earlier, more accessible, and more precise detection and treatment of the world’s most prevalent neurodegenerative disease.

Trontinemab shows rapid amyloid clearance with low ARIA risk

SHERIDAN, WYOMING – July 29, 2025 – Roche’s gene therapy for Duchenne muscular dystrophy (DMD), Elevidys™ (delandistrogene moxeparvovec), has encountered a regulatory hurdle in the European Union, following a negative opinion from the EMA’s Committee for Medicinal Products for Human Use (CHMP). While disappointing, the decision does not mark the end of the road for the therapy, which remains the first and only disease-modifying gene therapy available for DMD and continues to show promise in stabilizing disease progression in ambulatory patients.

First-in-class gene therapy meets complex regulatory path

The CHMP’s negative stance was issued in response to Roche’s application for conditional marketing authorization (CMA) of Elevidys for ambulatory children aged 3–7 with DMD. Roche has confirmed that it will continue dialogue with the EMA to explore a viable regulatory pathway.

SHERIDAN, WYOMING – July 29, 2025 – As tethered caps become the EU standard for PET bottles, German packaging systems leader KHS is turning to artificial intelligence to overcome the rising complexity of closure inspection in high-speed beverage production lines.

The company has equipped its widely used Innocheck TSI closure inspection system with a new AI-powered module designed to identify defects in real time with greater precision. Developed with patent-pending deep learning algorithms, this innovation represents KHS’s strategic move toward smarter, adaptive quality control at scale.

Smarter Inspection for Complex Cap Variants

SHERIDAN, WYOMING – July 29, 2025 – A landmark achievement in aseptic beverage packaging has been reached as Hauser Weinimport, a leading German copacker, announces the successful production of over 600 million PET bottles using Sidel’s pioneering Combi Predis™ system. Installed 15 years ago, this dry preform sterilisation solution remains one of the most enduring examples of aseptic innovation in beverage manufacturing.

Pioneering aseptic PET packaging with long-term ROI

Hauser Weinimport was Germany’s first adopter of Sidel’s Combi Predis™ aseptic PET line, featuring dry preform sterilisation using hydrogen peroxide mist. Unlike conventional aseptic processes that rely on rinsing with chemicals or water, Predis enables bottle sterilisation before blowing, maintaining aseptic conditions while significantly reducing environmental impact.

SHERIDAN, WYOMING – July 29, 2025 – Grupo GEPP, the exclusive bottler for PepsiCo in Mexico, has significantly expanded its returnable PET and glass packaging infrastructure with support from Sidel, reinforcing its long-term strategy to reduce virgin plastic use and align with PepsiCo’s global sustainability roadmap.

The collaboration focuses on scalable returnable bottling solutions—critical for achieving PepsiCo’s stated target of doubling returnable packaging from 10% to 20% by 2030 while cutting first-use plastic per serving in half. Through Sidel’s advanced filling and washing systems, GEPP is setting a new benchmark in circular packaging at scale across the Latin American beverage market.

Returnable packaging systems built for circularity and operational flexibility

SHERIDAN, WYOMING – July 29, 2025 – In a landscape defined by evolving dental materials, Dentsply Sirona’s AH Plus® continues to set the standard in endodontic sealing—celebrating 30 years of clinical trust, scientific validation, and global use across more than 800 million root canal procedures.

Three Decades of Clinical Consistency and Scientific Validation

Originally launched in Europe in 1995, AH Plus® has become the most extensively researched endodontic sealer on the market. To mark its 30th anniversary, Dentsply Sirona has published a comprehensive scientific manual showcasing peer-reviewed studies that confirm its efficacy across diverse obturation techniques and clinical scenarios. Spanning data from over 3,400 patients and nearly 3,800 teeth, the manual strengthens the product’s legacy as a benchmark material in endodontics.

Workflow Reliability Through Proven Chemistry

SHERIDAN, WYOMING – July 29, 2025 – Dentsply Sirona has appointed veteran medtech executive Daniel Scavilla as President and Chief Executive Officer, effective August 1, 2025, in a leadership move designed to accelerate its ongoing transformation, deepen innovation, and unlock new commercial opportunities across the global dental market.

A leadership shift with proven operational impact

Scavilla joins the executive ranks from within Dentsply Sirona’s Board of Directors, where he has served since February 2025. His appointment follows the planned departure of outgoing CEO Simon Campion, who concludes his three-year tenure on July 31. With over 30 years of experience spanning Johnson & Johnson and Globus Medical, Scavilla brings a track record of leading major integrations, scaling commercial infrastructure, and advancing market leadership positions.

SHERIDAN, WYOMING – July 29, 2025 – Dentsply Sirona is doubling down on its commitment to delivering more than just clinical education at DS World Las Vegas 2025 by unveiling a headline entertainment and speaker roster that blends celebrity impact with entrepreneurial insight. Taking place September 25–27 at the MGM Grand, this flagship event will feature Emmy-winning comedian Dana Carvey, Grammy-winning musician Sheryl Crow, and OrangeTheory co-founder Ellen Latham in a format designed to inspire, entertain, and empower the global dental community.

Entertainment that Builds Connection and Culture

SHERIDAN, WYOMING – July 29, 2025 – Dentsply Sirona is redefining digital chairside workflows with the next evolution of its iconic CEREC system, now seamlessly integrated into the DS Core cloud platform. Celebrating four decades of continuous innovation, the CEREC system combines precision dentistry with real-time digital collaboration—enabling practices to deliver same-day restorations faster, more efficiently, and with greater patient engagement than ever before.

A 40-Year Legacy Meets Modern Cloud Dentistry

Launched in 1985, CEREC (Chairside Economical Restoration of Esthetic Ceramics) pioneered single-visit restorations. Today, its integration with DS Core marks a significant milestone in connected dentistry. This cloud-based platform centralizes intraoral scans, design data, material selection, and production control—allowing clinicians to move seamlessly from scanning to milling with remote access and streamlined workflows.

SHERIDAN, WYOMING – July 29, 2025 – Bio-Rad Laboratories has named Rajat Mehta as its new Executive Vice President of Global Commercial Operations, signaling a strategic push to accelerate growth across its diagnostics and life sciences business lines. Mehta, whose appointment takes effect August 4, 2025, brings broad cross-sector expertise and a proven track record of commercial execution in the biopharma and scientific instrumentation industries.

New commercial leadership aimed at scaling global market impact

With over two decades of experience spanning Labcorp, Thermo Fisher Scientific, and Dow Chemical, Mehta is positioned to enhance Bio-Rad’s commercial alignment across geographies and market verticals. His appointment follows the planned retirement of industry veteran Mike Crowley, who has served in senior roles at Bio-Rad since 1998 and helped shape its global sales infrastructure over the past decade.