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SHERIDAN, WYOMING - December 15, 2025 - Dubai Airshow 2025 opened at Dubai World Central with the Middle East debut of two of China's homegrown C919 aircraft, signaling a higher-profile push by Chinese aerospace players to showcase commercial, unmanned, and next-generation aviation technologies to global buyers.

C919 debut puts China's narrowbody on a new international stage
At the 19th edition of the Dubai Airshow, the appearance of the C919 marked its first showing in the Middle East, with a flight demonstration at the venue. The aircraft's presence matters beyond the air display: for airlines, lessors, MRO providers, and airport stakeholders, international showcases help shape early market perception around supply-chain maturity, support ecosystems, and longer-term export ambitions.

SHERIDAN, WYOMING - December 15, 2025 - ARIDGE has introduced new details on its next-generation A868 flying car concept and confirmed fresh progress at its flying car manufacturing plant, as the company positions two flight systems to serve different segments of China's emerging low-altitude mobility market.

Two flight systems target distinct low-altitude travel needs
ARIDGE framed the low-altitude economy as the next major growth frontier following new energy vehicles, and outlined a dual-product strategy built around different operating missions. The company is developing:

SHERIDAN, WYOMING - December 15, 2025 - XPENG AEROHT has completed a public manned flight of its modular flying car, the "Land Aircraft Carrier," in Dubai and signed purchase agreements totaling 600 flying cars across the Middle East, as the company accelerates overseas expansion and rebrands as ARIDGE.

Dubai manned flight pairs technology validation with commercial traction
The October 12 milestone combined a fully manned demonstration flight with what the company described as record-breaking regional demand, lifting total global orders to over 7,000. The event was witnessed by regional dignitaries, members of the local Chinese community, and more than 100 media outlets, signaling both regulatory interest and market visibility as the "low-altitude economy" shifts from concept showcases to procurement discussions.

SHERIDAN, WYOMING - December 15, 2025 - XPENG AEROHT has secured a manned aircraft special flight permit from the UAE's General Civil Aviation Authority (GCAA) for its modular flying car "Land Aircraft Carrier" in Ras Al Khaimah, enabling manned flight tests across the country and marking a notable step in the overseas commercialization of China's low-altitude eVTOL technology.

Aviation permission becomes a market-entry signal for advanced air mobility
The permit, granted in Ras Al Khaimah, is positioned as the first such authorization obtained by a Chinese flying car company overseas. For B2B stakeholders-from mobility operators to public-sector agencies-regulatory access is often the gating factor that turns "future mobility" narratives into measurable pilots, procurement conversations, and infrastructure planning.

SHERIDAN, WYOMING - December 15, 2025 - XPENG AEROHT, the flying car affiliate of Chinese EV maker XPENG, has begun trial production at what it describes as the world's first intelligent factory for mass-produced flying cars-an operational milestone as next-generation mobility moves from prototypes to industrial output.

Trial production signals a commercialization inflection point
The company started trial production on November 3, 2025, positioning the facility as a bridge between engineering validation and repeatable manufacturing. For the broader eVTOL and "low-altitude mobility" ecosystem, factory readiness matters because it shifts the discussion from flight demonstrations to supply chains, quality systems, and scalable assembly-areas that typically determine whether new vehicle categories can reach customers on schedule.

SHERIDAN, WYOMING - December 15, 2025 - Shanghai is sharpening its push to become a leading center for merger-and-acquisition activity, as the 2025 Mergers and Acquisitions Finance Conference spotlighted stronger regional deal momentum and unveiled a new market index intended to track China's evolving M&A environment.

Policy momentum behind listed-company restructuring
The conference took place as Shanghai marks one year since releasing a three-year action plan aimed at supporting M&A among listed firms. In practical terms, the message to corporate leaders and capital providers is clear: policy alignment and financial-market infrastructure are being positioned to support more transactions that improve efficiency, accelerate industrial upgrading, and strengthen competitiveness in key sectors.

SHERIDAN, WYOMING - December 11, 2025 - The FDA's first use of its new Commissioner's National Priority Voucher (CNPV) has gone not to a cutting-edge biologic, but to a decades-old extended-release antibiotic, Augmentin XR-sending a clear signal that domestic manufacturing and supply resilience are now front-and-center regulatory priorities for the U.S. pharmaceutical industry.

A New Fast-Track Tool Aimed at Supply Chain Security

Launched in June, the CNPV program promises to compress review timelines from the usual 10-12 months to as little as 1-2 months for drugs that align with U.S. "national priorities," such as strengthening domestic production or addressing systemic shortages. The first approval under this framework went to USAntibiotics' Augmentin XR after the FDA completed its review in "just two months," focusing heavily on quality, manufacturing and facility assessments rather than new clinical data.

SHERIDAN, WYOMING - December 11, 2025 - A new convergence of obesity dealmaking, regulatory uncertainty at the U.S. Food and Drug Administration (FDA) and fresh neurology data out of the Clinical Trials on Alzheimer's Disease (CTAD) conference is forcing biopharma executives to recalibrate their 2026 playbooks across R&D, partnering and risk management.

Obesity Dealflow Enters a More Competitive, High-Stakes Phase

Pfizer continues to double down on cardiometabolic disease, following its $10 billion acquisition of obesity startup Metsera with an exclusive collaboration to license YaoPharma's oral GLP-1 receptor agonist YP05002. Together with other emerging oral and peptide GLP-1s, this next wave of assets is pushing obesity beyond a single-product, single-modality market and into a diversified, highly competitive landscape.

SHERIDAN, WYOMING - December 11, 2025 - Saol Therapeutics is turning an FDA rejection into a potential regulatory test case, as the biotech prepares to argue that its pyruvate dehydrogenase complex deficiency (PDCD) drug SL1009 is the ideal "poster child" for the agency's new Rare Disease Evidence Principles (RDEP) framework at a Type A meeting on December 18.

Saol Recasts a Complete Response Letter as a Strategic Opening

On September 8, Saol disclosed that the FDA had issued a complete response letter (CRL) for SL1009, an oral formulation of sodium dichloroacetate for children with PDCD, a genetic disorder affecting fewer than 1,000 people in the U.S. The CRL, according to CEO Dave Penake, "suggested that we would need to do an additional adequate and well controlled clinical trial," and that "and that's not feasible to be done by our company and in this patient population."

SHERIDAN, WYOMING - December 11, 2025 - Terns Pharmaceuticals is rapidly emerging as a serious contender in chronic myeloid leukemia (CML), after early clinical data for its allosteric BCR/ABL1 inhibitor TERN-701 more than doubled response rates seen with Novartis' approved STAMP inhibitor Scemblix in comparable settings and sent the biotech's share price sharply higher.

Best-in-Disease Early Efficacy Raises the Bar in CML

At the American Society of Hematology (ASH) annual meeting, Terns reported Phase I data from the CARDINAL trial in previously treated CML patients, with 38 participants evaluable for efficacy. TERN-701 achieved a major molecular response (MMR) rate of 75% at week 24, with 64% of patients reaching MMR overall in the dataset presented. The investigational agent also supported simple once-daily dosing without a food effect, improving convenience relative to many existing tyrosine kinase inhibitor (TKI) regimens.